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Day: 5 October 2014

Live: Will and the People

19th September

Antwerp Mansion

Will and the People have become a new found favourite in my collection after what can only be described as an awesome gig at Manchester’s Antwerp Mansion, blasting their euphoric fusion of reggae, ska, pop and punk until the early hours of the morning and leaving the audience literally begging for more. The British 4-piece have been touring on the back of their recently released third album, Whistleblower, showing off both familiar and new material to their growing fan base. The band took to the stage around midnight after the incredible opening act Salutation Dub Collective, a Manchester based band that absolutely smashed it with a combination of hilarious anecdotes and fantastic music.

Will and the People had the crowd swaying back and forth to the mellow opening track “Sensimilla” before ramping up the tempo and bursting into an energetic rock and roll take on the track that definitely opened any sleepy eyes. Coming into the gig I was highly anticipating their two most successful singles; the catchy feel-good tracks “Lion in the Morning Sun” and “Salamander,” and was rewarded when they dropped one after the other, the entire crowd singing along to every word. Energy levels reached their peak with a cover of The Pixies’ “Where Is My Mind,” immediately sending the crowd into a sweaty frenzy of flailing limbs and madly grinning faces, before leading into a reggae-style interpretation of the song to calm the revellers. The chants for “one more song” dragged the band back to stage not once, but twice – a sure sign of an unforgettable set.

On leaving the gig a tenner lighter and an album heavier, an immediate purchase from the merch stand on the way out, I realised I had witnessed one of the best live performances of my life so far. The effect that Will and the People have on their audience is immense, with every song generating a positive response. The band’s capability to effortlessly blend genres into one another to create unique and dynamic music is one of the reasons why Will and the People are not a band to be overlooked.

Combining cancer treatments could improve survival rates in patients

A new treatment developed by scientists at the University of Manchester could seriously improve the survival rates for patients undergoing radiotherapy treatment for cancer.

By treating patients with both radiotherapy and immunotherapy, the risk of cancerous cells becoming resistant to treatment could be eliminated.

The researchers found that combining the two treatments helped the immune system to track down and kill cancerous cells that survived the first bout of radiotherapy. The test subjects were mice suffering from cancer of the breast, skin and bowel.

Radiotherapy is a well-known method of killing or controlling malignant cells. More than half of all cancer patients undergo the treatment. For many types of cancer it is very successful, but any cancer cells that it fails to kill can become resistant to it. The treatment can switch on a ‘flag’ on the surface of an unaffected cell, called PD-L1. This tricks the body into thinking that the cancerous cells are harmless.

Immunotherapy works by injecting an antibody into the blood stream, which blocks the ‘flags’ and alerts the body to the danger posed by the cells. The immune system then kicks into play and destroys them. In this series of experiments, it was found that the combination of the treatments protected the mice from the possibility of the disease returning.

The lead researcher, Dr Simon Dovedi, who is also a member of the Manchester Cancer Research Centre, said: “Using the body’s own defences to treat cancers has huge potential with early phase clinical trials demonstrating exciting patient benefit but we are still at the early stages of understanding how best to use these types of treatments.

“Combining certain immunotherapies with radiotherapy could make them even more effective and we’re now looking to test this in clinical trial to see just how much of a difference it could make.”

The chief clinician of Cancer Research UK, Professor Nic Jones, said: “Around half of all cancer patients are given radiotherapy and it has been at the heart of helping improve survival rates so that today one in two cancer patients will survive for at least ten years.

“Doctors and researchers are constantly looking for ways to improve treatments and this approach could open the door to a whole new way of giving radiotherapy.”

The work undertaken by the researchers was funded by MedImmune, a subsidiary of AstraZeneca specialising in biotechnology. The Director of Oncology Research at the company, Dr Robert Wilkinson, said: “MedImmune is committed to developing strong science led collaborations, and supporting research that helps further advance our scientific understanding in the important area of immunotherapy. The findings described in the recent study with Cancer Research UK are extremely encouraging.”

Teenage girl-gang’s seven-month violence spree comes to an end

A gang of teenage girls have been jailed for victimizing young female students around the Wilmslow Road and Fallowfield area of Manchester in a series of physical assaults and violent robberies.

A Manchester Crown Court sentencing hearing was told, “Female revellers and university students were targeted in night-time street attacks on Wilmslow Road and its outskirts during the gang’s seven-month crime spree.”

In a string of attacks from September 2013 to April 2014, the gang followed its victims on the Wilmslow Road late at night and brutally assaulted them in isolated areas, after binging on vodka.

In one of their many confrontations, five women in Fallowfield were followed, grabbed by their hair and dragged to their knees before being repeatedly punched and kicked by Margaret Grey and Zara Hussain.

On the same night, three hours later, another female was targeted in the same area when the gang charged at her and stole her phone, ripping her earring out and left her splattered in blood on the street.

While on bail two-and-a-half months later, Margaret Grey, Daniella Hodge and Chloe Minchion beat up another group of female University of Manchester students, before escaping with one of their bags in the Victoria Park.

Four months after their last violent burglary, Grey and Hussain, again while on bail, were involved in a hit-and-run incident with a shopkeeper. The shopkeeper later told the police that he was “terrified” of the pair, who punched him ten times in the face and directed racial slurs at him.

Margaret Grey, 18, from Meade Grove, Longsight, has been jailed for 32 months and barred from seeing the other three girls by an ASBO after admitting two robberies, two attempted robberies, and racially aggravated assault. Zara Hussain, 20, from Burnage, was served with a 20-month sentence after admitting robbery and attempted robbery. Daniella Hodge, 18, from Openshaw, was given a two-year community order with supervision and a requirement to attend a probation service programme for robbery and attempted robbery.

Chloe Minchion, who recently gave birth to a child, is wanted by police after her absence at the Manchester Crown Court for sentence for her involvement in same offenses.

Crown Court Judge Robert Atherton dismissed their insistence of regret, saying: “The victims of all those robberies were young women going about enjoying themselves and minding their own business. You fall into that group of people who go out, get drunk, misbehave, and say ‘I’m terribly sorry, I was drunk, I’ve had a bad upbringing, I didn’t mean it.’”

You Can’t Handle the Truth! – New Girl

There are so many things in life I am simply incapable of understanding.

Why some young men wear tank tops in public, how Smells Like Teen Spirit is regarded as a brilliant song and why people care so much about what the Kardashians are doing. The list is endless; I could go on for hours.

But one thing that makes me want to both laugh and cry at the same time is how people of my generation are too busy worshipping the pseudo-intellectual, non-funny The Big Bang Theory to realise another show currently in its fourth season is easily the greatest sitcom since Friends. I could go even further, but I am afraid of death threats from Team Aniston. I am talking about New Girl.

It is obviously important to acknowledge that most sitcoms today, New Girl included, would not have existed if it wasn’t for Friends and its impact on television, but New Girl was such a quirky breath of fresh air when it first premiered. The show is simply about Jess, portrayed by the beautiful Zooey Deschanel, who decides to move into an apartment with three strangers after her boyfriend cheated on her. Deschanel is talented, famous and very pretty, so she should be the star here, right?

Well, she’s not. The future Academy Award-winner Max Greenfield runs the show from the very first episode. He portrays Schmidt, a highly quotable Jewish narcissistic womaniser with OCD, who in the hotter months orders personalised citrus-flavoured condoms for a more ‘refreshing summer experience’. It took Barney Stinson seven seasons in HIMYM to become what Schmidt was from the start: a solid, three-dimensional character. I could write a book about Schmidt, his driving moccasins and his croquet cleats, but Greenfield’s character isn’t the only reason why New Girl is the funniest, most quotable show on television these days. One episode is simply about how everyone lost their virginities, and Winston, a black puzzle enthusiast and ex-basketball player in Latvia also living in the same apartment, realises his first lover was a prostitute. Visibly traumatised and in the fetal position, he delivers the best quote of the show yet, asking the room: “Was Mysteria even her real name?”

New Girl’s screenplay is unique and charmingly hilarious, and I am certain that the show, in a few years time, will get the recognition it deserves.

PARKOUR!

Man in serious condition after Fallowfield attack

A man is in a serious condition after being attacked outside the Shell Garage on Wilmslow Road in the early hours of last Tuesday morning.

The 51-year-old cycled to the garage to buy some cigarettes and was approached by another man who took his bike from him. He was then punched several times and pulled to the ground where he was kicked in the head.

The cyclist was left with serious head injuries and is currently in a stable condition in hospital.

Detective Inspector Adrian Gallagher from Greater Manchester Police said: “At this stage, it appears there was an argument over the ownership of the bicycle which has resulted in a nasty assault.

“The man is very poorly in hospital and is currently receiving treatment for a fractured skull and a bleed on the brain.

“We have already spoken to a number of witnesses who were at the Shell Garage at the time of the offence, but there were others who we have not yet identified.

“We are urging anyone who witnessed this attack to come forward to police and tell us what you saw.”

A 46-year-old man has been arrested on suspicion of assault and remains in custody.

Greater Manchester Police are appealing for witnesses of this attack and anyone with information should call the police on 0161 856 4973 or the independent charity Crimestoppers anonymously on 0800 555 111.

“Viva the Republic of Mancunia”

Greater Manchester Combined Authority (GMCA) responded last week to the Prime Minister’s reference to greater devolution for England’s larger cities in the wake of the Scottish referendum results.

The Prime Minister said, “it is important that we have wider civic engagement about how to improve governance in our United Kingdom, including how to empower our great cities. And we will say more about this in the coming days.”

Lord Peter Smith, Chair of Greater Manchester Combined Authority, said “We welcome the Prime Minister’s words about the need to empower our great cities… Greater Manchester has the experience and capability to move quickly.

“Greater Manchester has a bigger economy than Wales or Northern Ireland, and a population of almost three million, yet we have considerably less freedom over our funding and spending priorities.”

ResPublica, an independent public policy think tank published a report prior to the Scottish referendum outlining a blue print for full devolution for English cities, using Greater Manchester as the case in point.

The report ‘Devo Max – Devo Manc’ outlines the case that the GMCA with an elected major and assembly, as is the model in London, could have control over such things as property and income taxes.

“We put forward Greater Manchester for full place-based integration of public sector spend because with its well evidenced growth potential and mature governance structures, it is one of the few places in the UK that could pilot devolution on this scale.”

According to Scott Fletcher MBE, of ANS group, the report by ResPublica makes perfect sense. In a recent statement he said, “Manchester is in a commanding position at the moment. High tech companies and aspiring entrepreneurs aren’t confined solely to London and, indeed, often find more fertile ground elsewhere, such as Manchester and the North West.”

He added “Manchester is a vibrant and growing city and if we get the devolution of power that appears to now be politically possible then our great city and the wider North West can only benefit, giving us powers over a wide range of issues such as health, education and business support. I say bring it on, viva the Republic of Mancunia.”

Lord Smith added that he believes Manchester is “uniquely well-placed to demonstrate the benefits of greater freedom to make decisions and funding allocations which will help the region realise its full potential.”

We need the freedom to make decisions on funding and priorities based on the area’s needs, not the ‘one size fits all’ approaches handed down from Westminster and Whitehall.”

Ed Miliband proposes, as outlined in his speech at last week’s Labour conference in Manchester, “devolving power to local government, bringing power closer to people right across England” adding “It’s got to be led by the people. It can’t be a Westminster stitch-up.”

At the Labour party conference last week, ten city leaders signed a letter to the first Secretary of State William Hague asking for speedy devolution to cities across the UK.

The eight English Core Cities—Birmingham, Bristol, Liverpool, Leeds, Manchester, Newcastle, Nottingham and Sheffield—have recently been joined by Cardiff and Glasgow, forming ‘Core Cities UK’.

The leaders welcome the Prime Ministers recent promises of more ‘empowered’ UK cities. But they say ‘our communities, our voters, will not accept delay based on constitutional wrangles, or half measure delivered through political compromise.”

In the letter issued to Hague the leaders outline that the “ten Core Cities deliver 28% of the English Welsh and Scottish economy.”

By 2030, the original eight English Core Cities alone could put 1.16 million jobs and £222 billion extra into the economy.” which they added is “like adding the entire economy of Demark to the UK—with Glasgow and Cardiff onside it will be even more.”

However these improvements they say “cannot be met by our heavily centralised and overly bureaucratic systems of investment.”

The leaders added that the “timing should not restrict the promises to Scotland being delivered” but that the “the people of Scotland have decided that devolution and Union are not incompatible, and neither is local freedom and national growth.”

Manchester Evening News reported that Lucy Powell, MP for Manchester Central thinks “we are ready” for devolution but that we must first tackle the problem of poor election turnouts.

The report highlighted that Ms. Powell was elected after a turnout of just 18 per cent in 2012. However she believes that the referendum with an 84.6 per cent turnout demonstrated people will engage in politics if they feel they have control over the places they live.

Council sets up Manchester Dogs’ Home task force

Since the Harpurhey dog centre fire on 11th September 2014, which left 60 animals dead and large sections of the premises destroyed, Manchester City Council has set up a joint task force to ensure that the Manchester Dogs’ Home is back up and running as soon as possible.

The joint task force, including technical officers from the city council and charity trustees, has been organised to plan the redevelopment of the kennels which have been a cherished part of the Manchester Community for over 115 years.

Manchester City Council has played a key role in aiding the Dogs’ Home including organising a clean-up operation. Not only has the Council provided immense support since the blaze, members of the public have also shown interest, donating tonnes of supplies currently being held in city council storage facilities.

Further, generous celebrity donators including Simon Cowell, Ricky Gervais, and Piers Morgan have also pledged to the cause, with so far over £1.4 million having been raised.

One week after the blaze, the Dogs’ Home released a statement, thanking the public and saying that they hope “that the re-build of the site will enable us to incorporate the very latest developments in canine welfare to make Manchester Dogs’ Home even better than before.”

City council members also added to the statement. Councillor Pat Karney, leading the City Council’s support for the dogs’ home, said: “We’re here for the duration, and we’ll be working closely alongside the charity while the new centre is being rebuilt.”

Councillor Bernard Priest, deputy leader of Manchester City Council, said: “In this emergency situation we’re offering support and assistance to help in any way we can, and this includes setting up a task force to make sure the home is back up and running as quickly as possible.”

Meanwhile the dog home heroes Jason Dyer and Dean Rostock, who entered the building whilst it was still ablaze to save trapped dogs have been nominated for a prestigious Animal Hero Award which recognises the most inspiring examples of bravery, dedication and resilience in the animal world.

Students Raise £230k for charity

Students across Manchester rose over £230,000 for British Heart Foundation (BHF) by giving away unwanted items as they left for the summer.

Manchester City Council joined forces with universities and the British Heart Foundation to run this campaign.

Charity collection bags were distributed to students and they were encouraged to donate any unwanted items normally left for the rubbish.

Almost 17,000 bags were collected this summer—almost double that collected last year in the same campaign.

The items ranged from books, shoes and clothing to hairdryers and rice cookers. All the funds raised from the sale of these have gone to The British Heart Foundation which fights one of the UK’s biggest killers.

The scheme began in 2009 and it aims to both encourage students to take responsibility for their belongings and be charitable students.

The Council, University representatives and the BHF have all been very vocal in their gratitude towards the charitable heart shown by the students across Manchester.

Councillor Bernard Priest, Manchester City Council’s deputy leader, said: “The amount that was collected this summer was truly staggering, and it’s a tribute to the efforts of Manchester students that so many items will all now go to help fight one of the UK’s biggest killers.”

Sophie Leigh, Manchester Metropolitan University’s Sustainability Engagement Manager, said: “We are thrilled that this initiative has raised such a fantastic amount of money for a very worthy cause and helped to make the city greener at the same time.

Our students really embraced the idea of recycling their unwanted possessions for charity, and we hope this campaign will go from strength to strength.”

Alexander Clark, Environmental Coordinator at The University of Manchester, said: “Each year more and more of our students actively engage with this campaign, which is great to see how many students understand the importance of supporting charities.

“It is a very busy time during the end of year, but the fact that students take their responsibilities to donate unwanted items instead of landfilling them is a great step forward for the city.”

Catherine Argyle, BHF Regional Stock Generator, said: “We’ve been delighted with the response from students and residents in Manchester and their overwhelming support.

“Each BHF shop needs to receive 400 bags of unwanted items a week and thanks to generous donations from the residents, students and university staff in Manchester, we have been able to help our shops in the city.

“Coronary heart disease is the UK’s single biggest killer, shattering the lives of too many children, parents and grandparents.”

Manchester scientists synthesise “Star of David” molecule

In the culmination of over a quarter of a century’s work, a Ph.D. student at the University of Manchester’s School of Chemistry has successfully created a molecule whose atomic structure perfectly matches the shape of the ‘Star of David’ symbol.

This unique particle, the most complex of its kind ever produced, is built from two interweaving triangular molecules, each containing just 114 atoms. The triangles are entwined about each other three times, forming a hexagram. The process by which the triangles were weaved around each other at the same time as their formation, called self-assembly, is not too dissimilar to how the double helix is formed in DNA molecules.

The molecule was created by Ph.D. student Alex Stephens and details of the synthesis were published in the journal Nature Chemistry.

Professor David Leigh of the School of Chemistry said: “It was a great day when Alex finally got it in the lab.

“In nature, biology already uses molecular chainmail to make the tough, light shells of certain viruses and now we are on the path towards being able to reproduce its remarkable properties.”

The research team are not stopping here though, and hope to go on to synthesise even larger and more elaborate molecules in the future. Professor Leigh expressed his belief that this is just further progress towards creating materials with exciting new properties that could have some very interesting applications.

“It’s the next step on the road to man-made molecular chainmail, which could lead to the development of new materials which are light, flexible and very strong. Just as chainmail was a breakthrough over heavy suits of armour in medieval times, this could be a big step towards materials created using nanotechnology. I hope this will lead to many exciting developments in the future.”